Abstract #3211
Rapid 2D variable flip angle (VFA) T1 mapping using sharp slice profiles
Matthias Alexander Dieringer 1,2 , Jeanette Schulz-Menger 2 , and Thoralf Niendorf 1,2
1
Berlin Ultrahigh Field Facility (B.U.F.F.),
Max-Delbrueck Center for Molecular Medicine, Berlin,
Germany,
2
Experimental
and Clinical Research Center (ECRC), Charit Medical
Faculty and Max-Delbrueck Center for Molecular Medicine,
Berlin, Germany
2D variable flip angle (VFA) T1 mapping has been
proposed for rapid T1 quantification. RF pulse
imperfections evoke non-uniform excitation flip angle
distributions that deem T1 quantification with 2D VFA
inaccurate. Sharp and uniform slice excitations could
render considerations on complex slice profile
corrections obsolete and could afford a direct T1
calculation of using simple gradient echo signal
equations. In this work, we use the minimum-time
variable-rate-selective-excitation (VERSE) algorithm to
produce high quality slice profiles in combination with
rapid two-point 2D VFA T1 mapping measurements in
phantom and in the human brain.
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