T1 mapping in the breast, with a Bloch-Siegert correction for variation in transmitted B1.
Mary McLean 1 , Andrew Patterson 2 , Reem Bedair 2 , Martin Graves 2 , Scott Reid 3 , John Griffiths 1 , and Fiona Gilbert 2
CRUK Cambridge Institute, University of
Cambridge, Cambridge, Cambridgeshire, United Kingdom,
Cambridge University Hospitals NHS Foundation Trust,
Cambridgeshire, United Kingdom,
Healthcare, Hertfordshire, United Kingdom
We implemented B1-corrected T1 measurements in the
breast, using the Bloch-Siegert method of B1 mapping and
DESPOT1. Orthogonal phase-encoding directions were
acquired to compensate for cardiac motion. Flip angles
higher than prescribed were consistently found to be
delivered on the left side, leading to artifactual
elevation in estimated T1. Compensation for B1 led to a
reduction in the magnitude of asymmetry (|L-R/R|) from
approximately 70% to 5% in both fat and parenchyma.
Following correction, average T1 was 1368 ms in breast
parenchyma and 458 ms in fat.
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