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Abstract #3212

T1 mapping in the breast, with a Bloch-Siegert correction for variation in transmitted B1.

Mary McLean 1 , Andrew Patterson 2 , Reem Bedair 2 , Martin Graves 2 , Scott Reid 3 , John Griffiths 1 , and Fiona Gilbert 2

1 CRUK Cambridge Institute, University of Cambridge, Cambridge, Cambridgeshire, United Kingdom, 2 Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridgeshire, United Kingdom, 3 GE Healthcare, Hertfordshire, United Kingdom

We implemented B1-corrected T1 measurements in the breast, using the Bloch-Siegert method of B1 mapping and DESPOT1. Orthogonal phase-encoding directions were acquired to compensate for cardiac motion. Flip angles higher than prescribed were consistently found to be delivered on the left side, leading to artifactual elevation in estimated T1. Compensation for B1 led to a reduction in the magnitude of asymmetry (|L-R/R|) from approximately 70% to 5% in both fat and parenchyma. Following correction, average T1 was 1368 ms in breast parenchyma and 458 ms in fat.

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