Myocardial Infarction Alters Dynamic Contrast Enhancement (DCE) Curve Shapes as well as Peak Enhancement: A Study using Plots of Myocardial vs. Blood Longitudinal Relaxation Rates

Myocardial fibrosis alters Gd-contrast agent dynamics. Myocardial partition coefficients calculated from a multipoint slope calculation will vary in healed myocardial infarction based on the selection of samples. This includes the use of pre-contrast measurements and samples early after contrast agent administration. Partition coefficient calculations are insensitive to data sampling effects in viable myocardium.

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