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Abstract #3242

Transverse Relaxometry for Brain Iron: Comparison of Seven Approaches

Md Nasir Uddin 1 , R Marc Lebel 1,2 , and Alan H Wilman 1

1 Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada, 2 Applied Science Laboratory, GE Healthcare, Calgary, Alberta, Canada

Quantitative transverse relaxation measurements and the low and field strengths difference measures can be used to assess iron levels in the human brain. We compared the R2, R2*, R2 and multi-slice FDRI mapping approaches for iron sensitivity measurements in deep gray matter using 1.5 T and 4.7 T. Results show R2* is most sensitive at iron at high field while R2 and FDRI provide specific brain iron measures.

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