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Abstract #3243

Phase Corrected Bipolar Gradients in Multiecho Gradient Echo Sequences for Quantitative Susceptibility Mapping

Jianqi Li 1 , Tian Liu 2,3 , Shixin Chang 4 , Fang Dong 1 , Hongwei Jiang 1 , and Yi Wang 2,3

1 Shanghai Key Laboratory of Magnetic Resonance and Department of Physics, East China Normal University, Shanghai, Shanghai, China, 2 Department of Biomedical Engineering, Cornell University, Ithaca, New York, United States, 3 Department of Radiology, Weill Medical College of Cornell University, New York, United States, 4 Department of Radiology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai, China

Multi-echo GRE sequences using bipolar readout gradients can offer efficient data acquisition for quantitative susceptibility mapping (QSM), but the bipolar gradient approach requires correction for phase errors. A simple linear phase correction in read-out direction is demonstrated in this study to allow accurate QSM in human brain using the bipolar multiecho GRE sequence. For all subjects and all ROIs studies, the bipolar multiecho acquisition provides good quantitative agreement with and reduces the noise in the unipolar acquisition.

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