Abstract #3280

3D MR Microscopy of Ex Vivo Retina Using Quantitative Susceptibility Mapping

Wei Li ^1,2 , Eric R. Muir ¹ , Bryan H. De La Garza ¹ , and Timothy Q Duong ^1,2

¹ Research Imaging Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States, ² Ophthalmology, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States

This study explored the use of high-resolution quantitative susceptibility mapping-based MRI microscopy for studying the highly stratified layers ex vivo rat retina at a spatial resolution of 23 x 23 x 57 lower case Greek mu

m ³ . Comparing to magnitude with weak contrast, both gradient echo phase and magnetic susceptibility shows remarkable contrast between different layers. These layered structures from phase and susceptibility is in good agreement with H&E staining using histology.

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