Abstract #3293
Prospective motion correction with EPI volume navigators for chemical exchange saturation transfer (CEST) imaging
Robert Frost 1 , Aaron T. Hess 2 , Nicholas P. Blockley 1 , Yee Kai Tee 3 , Michael A. Chappell 1,3 , M. Dylan Tisdall 4,5 , Andre J. W. van der Kouwe 4,5 , and Peter Jezzard 1
1
FMRIB Centre, Nuffield Department of
Clinical Neurosciences, University of Oxford, Oxford,
United Kingdom,
2
Department
of Cardiovascular Medicine, University of Oxford,
Oxford, United Kingdom,
3
Department
of Engineering Science, Institute of Biomedical
Engineering, University of Oxford, Oxford, United
Kingdom,
4
A.
A. Martinos Center for Biomedical Imaging, Massachusetts
General Hospital, Charlestown, MA, United States,
5
Radiology,
Harvard Medical School, Boston, MA, United States
Chemical exchange saturation transfer (CEST) is a
promising technique for treatment planning in acute
stroke. However, when using single-slice measurements,
the CEST acquisition is particularly susceptible to
through-plane patient motion, which cannot be corrected
in post-processing with 2D image registration. Here we
used prospective motion correction with 3D EPI volume
navigators to update the position of the imaging slice
in real time, with no increase in scan duration and
minimal effect on the image contrast. Maps of
magnetization transfer asymmetry were compared in cases
of no motion and deliberate motion to demonstrate the
improvement in data quality with prospective motion
correction.
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