Abstract #3296
Rapid PROPELLER-CEST Encoding with Background Asymmetry Subtraction for Ultrafast Z-Spectrum Acquisition
Hoonjae Lee 1 , Chul-Ho Sohn 2 , and Jaeseok Park 1
1
Department of Brain and Cognitive
Engineering, Korea University, Seoul, Korea,
2
Department
of Radiology, Seoul National University Hospital, Seoul,
Korea
In this work we propose a novel, rapid propeller-CEST
encoding with background asymmetry subtraction for
ultrafast z-spectrum acquisition, wherein 1)
off-resonant saturation and corresponding CEST encoding
are performed along the angular (blade) direction over
the entire k-space, 2) motion- and field-corrected
z-spectrum data is synthesized using only a single
k-space data (synthesize low frequency CEST signals
while sharing high frequency signals), and 3)
propeller-CEST encoding induced background asymmetry is
subtracted from the z-spectrum. It is expected that the
proposed method becomes a highly efficient alternative
to conventional CEST for rapid z-spectrum acquisition
and accurate CEST asymmetry analysis.
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