Meeting Banner
Abstract #3312

Scan-rescan reproducibility of parallel transmission based amide proton transfer imaging of brain tumors

Osamu Togao 1 , Takashi Yoshiura 1 , Jochen Keupp 2 , Akio Hiwatashi 1 , Koji Yamashita 1 , Kazufumi Kikuchi 1 , Yuriko Suzuki 3 , Koji Sagiyama 4 , Masaya Takahashi 4 , and Hiroshi Honda 1

1 Clinical Radiology, Graduate School of Medical Science, Kyushu University, Fukuoka, Fukuoka, Japan, 2 Philips Research Europe, Hamburg, Germany, 3 Philips Electronics Japan, Tokyo, Japan, 4 Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, Texas, United States

APT imaging is a specific type of endogenous CEST imaging technique. APT imaging can be useful in grading gliomas, diagnosing radiation necrosis, and evaluation of therapeutic effect. Observed signal changes in APT imaging is small and it can be influenced by the accuracy of saturation pulse and B0 inhomogeneity correction. We have developed a parallel RF transmission based technique, which allows arbitrarily long saturation pulses via amplifier alternation in clinical scanners. This method is combined with a special RF shimming for B1 homogeneity. In this study we assessed the reproducibility of this method in brain tumors by a scan-rescan test.

This abstract and the presentation materials are available to members only; a login is required.

Join Here