Abstract #3334
Assessing and Reducing the B 1 Dependence of Inhomogeneous Magnetization Transfer
Gopal Varma 1 , Olivier Girard 2 , Novena Rangwala 1 , Guillaume Duhamel 2 , and David C Alsop 1
1
Radiology, Division of MR Research, Beth
Israel Deaconess Medical Center, Harvard Medical School,
Boston, MA, United States,
2
CRMBM,
CNRS 7339, Aix-Marseille Universite, Marseille, France
The application of Inhomogeneous Magnetization Transfer
(IHMT) involves off-resonance saturation pulses, and as
such may be affected by RF field miscalibration or
non-uniformity. A measure of the B
1
dependence
from IHMT applied in the brain to a series of volunteers
suggests the IHMT contrast saturates at higher powers.
These results are used to develop a whole brain IHMT
sequence that appears less sensitive to RF field
non-uniformity when compared to an existing 3D spoiled
gradient-echo IHMT acquisition.
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