Abstract #3338
Fat Suppressed Modified Cross Relaxation Imaging of Articular Cartilage using MaTS: Magnetization Transfer Subtraction
Nade Sritanyaratana 1 , Pouria Mossahebi 1 , Walter Block 1 , Alexey Samsonov 2 , and Richard Kijowski 2
1
Biomedical Engineering, University of
Wisconsin-Madison, Madison, WI, United States,
2
Radiology,
University of Wisconsin-Madison, Madison, WI, United
States
Modified Cross relaxation imaging (mCRI) is a
quantitative magnetization transfer (MT) technique that
has been shown to provide potentially useful information
about cartilage degeneration. However, cartilage
imaging, especially in clinical settings, typically
requires large slice thicknesses (3-4mm) because
cartilages relatively thin tissue structure demands
high in-plane resolution (≈0.5mm). Especially since bone
and cartilage are significantly curved structures, this
highly anisotropic imaging scheme tends to increase
partial voluming, and in the context of quantitative
imaging can significantly corrupt parametric maps if not
corrected. Thus, we propose a technique that suppresses
partial voluming from fat and other MT non-exchanging
tissues. The proposed technique also suppresses fat
chemical shift artifacts, allowing for lower bandwidth
imaging for higher SNR.
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