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Abstract #3416

Patterns of Tissue Injury Detected by DTI Following Mild Traumatic Brain Injury

Andrew A. Maudsley 1 , Varan Govind 1 , Sulaiman Sheriff 1 , Gaurev Saigal 1 , and Bonnie Levin 2

1 Radiology, University of Miami, Miami, FL, United States, 2 Neurology, University of Miami, Miami, FL, United States

Diffusion-tensor imaging has been shown to be sensitive to diffuse axonal injury that is not observed using structural MRI. The locations of DTI-observed injury vary considerably between subjects, with the result that group-wise analyses indicate few associations with cognitive outcome. In this study maps representing the probability of tissue injury are generated, for a group of subjects with mild to moderate traumatic brain injury and association of summary measures with neurocognitive measures are evaluated.

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