Abstract #3433

Cerebral abnormalities in the gray matter volumes and metabolite concentration in patients with generalized anxiety disorder: voxel-based mormphometry and 1H-MRS

Chung-Man Moon ¹ and Gwang-Woo Jeong ^1,2

¹ Interdisciplinary Program of Biomedical Engineering, Chonnam National University, Gwangju, Gwangju, Korea, ² Radiology, Chonnam National University Hospital, Gwangju, Korea

Patients with generalized anxiety disorder (GAD) suffer the symptoms of psychological distress including excessive and uncontrollable anxiety about everyday things. These symptoms are assumed to be related with neural dysfunction or malfunction. The purpose of this study was to investigate cerebral abnormalities in the overall gray matter (GM) volumes and metabolite concentration in patients with GAD using the voxel-based morphometry (VBM) and localized 1H-MR spectroscopy (MRS).

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