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Abstract #3440

3D anatomical, functional, and blood flow MRI of the mouse retina and choroid with balanced steady state free precession

Eric R. Muir 1,2 and Timothy Q. Duong 1

1 Research Imaging Institute, University of Texas Health Science Center, San Antonio, TX, United States, 2 Department of Ophthalmology, University of Texas Health Science Center, San Antonio, TX, United States

MRI can provide anatomy, function, and physiology all in one setting, but its application to the thin retina has remained challenging. Most previous studies of the retina with MRI focused on 2D acquisitions with one relatively thick slice. However, there is interest in mapping the entire retina instead of a single 2D slice through the center. In this study, we developed a full 3D MRI approach with approximately isotropic resolution to image anatomy, function, and blood flow of the whole mouse retina and choroid in vivo with high spatial resolution based on balanced steady state free precession (bSSFP).

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