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Abstract #3455

Interoperator Dependence of Subject Specific CFD Modeling of Cerebrospinal Fluid Dynamics at the Craniocervical Junction

Theresia I. Yiallourou 1 , Mark Luciano 2 , Francis Loth 3 , Alexander C. Bunck 4 , Nikolaos Stergiopulos 1 , and Bryn A. Martin 5

1 Laboratory of Hemodynamics and Cardiovascular Technology, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland, Lausanne, --None--, Switzerland, 2 Department of Neurological Surgery, Cleveland Clinic Foundation, Cleveland, OH, United States, 3 Department of Mechanical Engineering, University of Akron, Akron, OH, United States, 4 Department of Radiology, University Hospital of Cologne, Cologne, Cologne, Germany, 5 Conquer Chiari Research Center, University of Akron, Akron, OH, United States

Detailed understanding of the pulsatile motion of the cerebrospinal fluid (CSF) and its importance to maintain brain health still remains enigmatic. 4D PC MRI flow measurements allow evaluating the complexities of the CSF flow patterns in diseases such as Chiari I Malformation. Computational fluid dynamics (CFD) simulations have provided detailed information about the CSF flow field. The first comparison of 4D PC MRI measurements to CFD of CSF flow in the craniocervical junction has recently been employed. This study aims to assess the inter-operator variability of the 3D rigid wall CFD simulations of the CSF flow in the craniocervical junction.

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