Detection of Human Neuronal Currents with Phase MRI

Brain activity-associated neuronal currents produce weak transient magnetic fields that would affect both magnitude and phase of the local MR signal. Recent studies show that the neuronal current-induced MR signal attenuation is too weak to be reliably detected with present magnitude MRI techniques. This study demonstrates that the visual stimulus-evoked neuronal currents in the visual cortex do not induce detectable phase signal changes either. The reduction of temporal phase noise level will be needed to achieve such detection.

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