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Abstract #3553

Role of Diffusion MRI in renal cell carcinoma: assessment of nuclear grade

Durgesh Kumar Dwivedi 1 , Girdhar Singh Bora 2 , Rajeev Kumar 2 , Sanjay Thulkar 3 , Sanjay Sharma 3 , Siddhartha Datta Gupta 4 , and Naranamangalam Raghunathan Jagannathan 1

1 Dept of NMR & MRI Facility, All India Institute of Medical Sciences, New Delhi, Delhi, India, 2 Dept of Urology, All India Institute of Medical Sciences, New Delhi, Delhi, India, 3 Dept of Radio-diagnosis, All India Institute of Medical Sciences, New Delhi, Delhi, India, 4 Dept of Pathology, All India Institute of Medical Sciences, New Delhi, Delhi, India

Recently there has been an annual increase of 2% in the incidence of renal cell carcinoma (RCC) worldwide. It is detected on computed tomography or ultrasound. Diffusion imaging has been shown to have potential in diagnosing various malignancies. We studied RCC lesions using diffusion-weighted MRI (DW-MRI). We found ADC values for RCC to be significantly lower than normal kidney tissue. Our results suggested that DW-MRI has potential in the prognostication of the patient and possibly could guide in therapeutic management.

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