Computed Diffusion-Weighted MR Imaging for Prostate Cancer Detection: Optimization of b-Value Combinations for Generating High b-Value Images.
Yoshiko Ueno 1 , Satoru Takahashi 1 , Kazuhiro Kitajima 1 , Yu Ueda 2 , Masamori Kassai 3 , Masao Yui 3 , Yoshiharu Ohno 1,4 , and Kazuro Sugimura 1
Department of Radiology, Kobe University
Graduate School of Medicine, Kobe, Hyogo, Japan,
of Radiology, Kobe University Hospital, Kobe, Hyogo,
Systems Development Department, Toshiba Medical Systems
Corp., Otawara, Tochigi, Japan,
Biomedical Imaging Research, Kobe University Graduate
School of Medicine, Kobe, Hyogo, Japan
Computed DWI (cDWI) is proposed as a new technique that
produces any b-value images from DWIs acquired with at
least two different b-values. However, it remains
unclear which combination of b-values is optimal for
generating high-b-value images. We hypothesize that
appropriate b value selection for cDWI can improve image
quality and detection capability on cDWI as compared
with actual DWI with ultra-high b value. The aim of this
study was to determine the appropriate b-value
combination for generating cDWI at b=2000 s/mm
improve prostate cancer detection, when compared with
actual DWI at b=2000 s/mm
a 3T MR system.
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