Are Respiratory Triggered Diffusion Weighted Acquisitions of the Liver Effective at Eliminating Respiratory Motion?

Diffusion weighted imaging (DWI) acquisitions of the liver are performed for lesion detection and characterization. Respiratory triggered acquisitions (RT) are used to eliminate anatomic misregistration caused by respiratory motion. To our knowledge, the effectiveness of RT strategies has not been explored. We analyzed the effect of respiratory motion on slice misregistration in DWI acquisitions. 74% of the DWI acquisitions in our study had at least misregistration in one of the 4 anatomic locations analyzed. Our results indicate that the utility RT DWI for lesion characterization in the liver may lack the robustness needed for broad applicability in clinical practice.

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