Abstract #3630
Optimizing b-value distribution for IVIM imaging using adjusted weighting factors
Sonia Isabel Goncalves 1 , Goncalo Cachola 2 , Filipe Caseiro-Alves 3,4 , and Miguel Castelo-Branco 1
1
IBILI-Faculty of Medicine, University of
Coimbra, Coimbra, Coimbra, Portugal,
2
Faculty
of Sciences and Technology, Universidade Nova de Lisboa,
Setubal, Portugal,
3
Faculty
of Medicine, University of Coimbra, Coimbra, Portugal,
4
Radiology,
University Hospital Coimbra, Coimbra, Portugal
Intra-voxel incoherent motion (IVIM) imaging
differentiates between true molecular diffusion,
diffusion due to perfusion, and quantifies perfusion
fraction. Results from its clinical application have
been ambiguous and this can be, at least in part,
explained by the dependence of IVIM parameter estimation
on the choice of b-value combination that is used to
sample the data. In this paper we explore the influence
of the perfusion rate regime in the total error
propagated into IVIM diffusion/perfusion parameters, in
order to optimize the b-value distribution that is used
to sample the data.
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