Abstract #3635
Changes in Choline Level and Lipid Profile in Rat Liver During Lipid Infusion Measured by Dynamic Proton MRS
Peng Cao 1,2 , Shu-Juan J. FAN 1,2 , Anna M. Wang 1,2 , Victor B. Xie 1,2 , Iris Y. Zhou 1,2 , and Ed X. Wu 1,2
1
Laboratory of Biomedical Imaging and Signal
Processing, The University of Hong Kong, Hong Kong, Hong
Kong SAR, China,
2
Department
of Electrical and Electronic Engineering, The University
of Hong Kong, Hong Kong, Hong Kong SAR, China
The liver proton MR spectroscopy (MRS) is typically used
for quantifying lipid content. Previous proton MRS
studies have reported the quantifications of liver lipid
profile and liver choline in vivo. This study aimed to
examine whether dynamic proton MRS can assess the time
courses of liver choline level and lipid profile in
response to the acute lipid intake. Our preliminary
results suggested that dynamic proton MRS could measure
the changes of choline level and lipid profile in normal
rat liver with acute intravenous lipid infusion.
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