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Abstract #3649

Utility of MR Elastography in Staging of Liver Fibrosis among Asia Patients with Chronic Liver Disease

Chen-Te Chou 1,2 , Ran-Chou Chen 3,4 , and Chih-Wei Lee 1

1 Chang-Hua Christian Hospital, Chang-Hua, Taiwan, Taiwan, 2 Biomedical Imaging and Radiological Science, National Yang-Ming Medical University, Taipei, Taiwan, Taiwan, 3 Radiology, Taipei city Hospital, Taipei, Taiwan, Taiwan, 4 Biomedical Imaging and Radiological Science, National Yang-Ming Medical University, Taiwan, Taiwan

According to the AASLD guidelines, aggressive treatment is advised for patients with hepatic fibrosis stages 2. Biopsy is the gold standard, but it is invasive. MR elastography (MRE) is a noninvasive method of measuring the hepatic viscoelastic properties. In our results, the stiffness values had a good correlation with the pathological fibrosis stage. In differentiation of fibrosis stage 2 from stage 0/1, the sensitivity and specificity were 93.4% and 91.0%, respectively, with a cutoff value of 2.83 kPa. MRE was a promising, noninvasive technique for prediction of fibrosis stage among Asia patients with chronic liver disease.

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