Abstract #3652
Wavelet Analysis of Liver Fibrosis
Zhitao Li 1 , Ali Bilgin 1,2 , Jean-Philippe Galons 3 , Puneet Sharma 3 , Diego Martin 3 , and Maria Altbach 3
1
Electrical and Computer Engineering,
University of Arizona, Tucson, Arizona, United States,
2
Biomedical
Engineering, University of Arizona, Tucson, Arizona,
United States,
3
Department
of Medical Imaging, University of Arizona, Tucson,
Arizona, United States
Chronic liver disease due to Hepatitis B/C or
non-alcoholic steatohepatitis is a major health problem.
The first manifestation of CLD is inflammation, which
can progress to fibrosis and cancer. Staging of liver
fibrosis requires an invasive liver biopsy with
associated morbidity, cost, and sampling errors. This
study is to investigate if structural changes of
fibrosis can be detected by localized frequency analysis
of liver images using wavelets. The work is carried out
in ex vivo tissue samples that resemble in vivo
Gd-enhanced images.
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