Physiological Bile Flow in the Extrahepatic Bile Duct: Evaluation with Cine-Dynamic MR Cholangiopancreatography and a Spatially Selective Inversion-Recovery Pulse
Minoru Hayashida 1 , Akihiko Kanki 1 , Akira Yamamoto 1 , Tsutomu Tamada 1 , Kazuya Yasokawa 1 , Daigo Tanimoto 1 , Atsushi Higaki 1 , Yasufumi Noda 1 , and Katsuyoshi Ito 1
Diagnostic Radiology, Kawasaki Medical
School, Kurashiki, Okayama, Japan
The purpose of this study was to determine the
feasibility of directly and noninvasively visualizing
physiological bile flow in the extrahepatic bile duct by
means of non-pharmacologic cine-dynamic MRCP with a
spatially selective inversion-recovery (IR) pulse and to
assess the flow dynamic pattern of bile in the
extrahepatic bile duct. Thirty-five patients without
known pancreatobiliary diseases and 11 patients with
dilatation of the extrahepatic bile duct were included.
Non-pharmacological, cine-dynamic MRCP with a spatially
selective IR pulse allowed direct and noninvasive
visualization of antegrade/reversed bile flow in the
extrahepatic bile duct, demonstrating that reversed bile
flow is a physiological phenomenon.
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