Non-invasive investigation of exocrine pancreatic function using cine dynamic MRCP with a spatially selective inversion-recovery (IR) pulse
KAUZUYA YASOKAWA 1 , AKIRA YAMAMOTO 1 , TSUTOMU TAMADA 1 , AKIHIKO KANKI 1 , ATSUSHI HIGAKI 1 , YASUFUMI NODA 1 , HIDEMITU SOTOZONO 1 , AYUMU KIDO 1 , AKANE UCHINO 1 , and KATSUYOSHI ITO 1
Radiology, Kawasaki Medical School,
Kurashiki, Okayama, Japan
This study investigated whether cine dynamic MRCP with a
spatially selective inversion recovery pulse can be used
for evaluation of exocrine pancreatic functions in 10
patients with suspected chronic pancreatitis in
comparison with currently available pancreatic exocrine
function test with N-benzoyl-L-tyrosyl-p-aminobenzoic
acid (BT-PABA) reagent. The urinary PABA excretion rate
(%) had significant positive correlations with both the
mean secretion grade (the distance that the pancreatic
juice moved in the pancreatic duct) and the frequency
that the pancreatic juice flowed in the pancreatic duct.
This technique has a potential to evaluate pancreatic
exocrine function noninvasively in patients with
suspected chronic pancreatitis.
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