Abstract #3668
Quantification of liver perfusion MRI with a time-signal curve fitting method
Lei Wang 1 , Sheng Xie 2 , YongLiang Sun 2 , ZhiYing Yang 2 , Jia Ning 3 , and HuiJun Chen 3
1
China-Japan Friendship Hospital, BeiJing,
BeiJing, China,
2
China-Japan
Friendship Hospital, BeiJing, China,
3
QingHua
University, BeiJing, China
Purpose: To analyze the perfusion measurements of the
liver with a simple method and to investigate the
correlation of clinical results with parameters. Methods
and materials: Patients with various levels of fibrosis
underwent perfusion MRI of the liver. The time-intensity
curves of MR signal from the perfusion MRI were analyzed
by linear fitting in segments. Tin, Tout ,Kup and ratio
were measured and compared between the S0-2 group and
S3-4 group. Results: A significant difference of each
parameter (Tin, Tout, Kup and Ratio) between two groups
was detected. Conclusion: The new procedure quantifies
the hepatocyte-specific uptake of the contrast agent.
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