A motion-robust sequence for combined thermometry and T2-mapping to guide and assess tissue damage during thermal therapies

Tissue damage is conventionally detected by thermal dose, which depends on heating history and can thus become fairly erratic in the presence of motion. The main purpose of this study was to detect tissue damage not only by thermal dose but also through changes in T2, in the presence of motion. We employed a dual-pathway sequence to simultaneously map temperature changes and T2 during focused ultrasound experiments that were performed in turn with or without motion. The presence of motion very much affected the phase-based temperature measurements but not nearly as much the magnitude-based T2 measurements.

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