Abstract #3676
Building Individualized 3D Anatomic Model Based on Prostate MRI for Hypothermia Bioheat Simulation
Peter T. Fwu 1 , Jeon-Hor Chen 1,2 , Yuting Lin 1 , Wei-Ching Lin 3 , Po-Jung Tseng 1 , Eddie Lin 1 , and Min-Ying Lydia Su 1
1
Tu & Yuen Center for Functional Onco-Imaging,
Department of Radiological Sciences, University of
California, Irvine, CA, United States,
2
Department
of Radiology, EDa Hospital and I-Shou University,
Kaohsiung, Taiwan,
3
Department
of Radiology, China Medical University Hospital,
Taichung, Taiwan
Regional hypothermia using endorectal cooling balloon (ECB)
during prostatectomy surgery is proven capable of
minimizing tissue inflammatory damages. In this work we
analyzed 29 prostate MRI cases. The images were
segmented to reconstruct a 3D anatomic model for each
patient for simulating the cooling processes by using
bioheat equation with finite element methods. Very
reasonable results were obtained, suggesting feasibility
of this approach. The temperature at neurovascular
bundle(NVB) was strongly affected by the distance from
the cooling balloon as well as the total venous blood
volume. For patients with similar blood volumes, the
temperature was linearly correlated with NVB-ECB
distance.
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