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Abstract #3678

Influence of magnetic susceptibility on absolute temperature as measured directly from the water/fat frequency shift.

Paul Baron 1 , Martijn de Greef 1 , Roel Deckers 1 , Chris J.G. Bakker 1 , Job G. Bouwman 1 , and Lambertus W. Bartels 1

1 University Medical Center Utrecht, Utrecht, Utrecht, Netherlands

During thermal therapies, measurements of the absolute temperature are needed to calculate the thermal dose. Deriving the absolute temperature directly from the water/fat(w/f) frequency difference has been proposed. The method assumes that the intra-voxel water and fat components experience the same magnetic field despite the fact that water and fat have slightly different magnetic susceptibilities. Here we investigate the influence of magnetic susceptibility distribution on the measured absolute temperature, both experimentally and with simulations. The results show a larger variation in measured temperature for a heterogeneous w/f distribution ( plus-or-minus sign 15C), such as the breast, than for a more homogenous distribution ( plus-or-minus sign 5C).

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