Real-time Quantitative Monitoring of Percutaneous MRI-guided Cryoablation of Renal Cancer

The safety and effectiveness of percutaneous image-guided ablations can be improved if the procedure could be assessed quantitatively. Using MRIs ability to depict both the tumor and the iceball during cryoablations, we developed a novel computerized tool that utilized fast automatic segmentation and registration methods to compute ablation metrics in MRI-guided cryoablations of renal cancer. The computer generated ablation metrics were compared to metrics calculated from manual segmentation of the tumor and the ablation zone in 24 hr MR images of same cases. Based on our experiments, the tool can provide accurate real-time quantitative assessment of key ablation metrics.

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