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Abstract #3692

Diffusion-weighted MRI using different b -value combinations for the evaluation of treatment results after volumetric MR-guided high-intensity focused ultrasound ablation of uterine fibroids

Marlijne Elisabeth Ikink 1 , Marianne J Voogt 1 , Maurice AAJ van den Bosch 1 , Robbert J Nijenhuis 1 , Bilgin Keserci 2 , Young-sun Kim 2 , Koen L Vincken 3 , and Lambertus W Bartels 3

1 Radiology, University Medical Center Utrecht, Utrecht, Utrecht, Netherlands, 2 Radiology and Center for Imaging Science, Samsung Medical Center, Seoul, Korea, 3 Radiology and Image Sciences Institute, University Medical Center Utrecht, Utrecht, Utrecht, Netherlands

DWI and ADC -mapping have been suggested for evaluation of treatment results after MR-guided high-intensity focused ultrasound (MR-HIFU) ablation of uterine fibroids. In well-perfused tissues, the ADC is known to reflect not only the diffusion of water, but also information about the perfusion in capillaries. The aim of this study was to investigate the optimal combination of b -values on the ADC . It was found that the combination of low b -values ( b = 0 and 200 s/mm 2 ) allows the best differentiation between ablated fibroid tissue and untreated tissue immediately after volumetric MR-HIFU ablation of uterine fibroids.

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