Abstract #3693
IntraVoxel Incoherent Motion MRI for the characterization of uterine fibroids before MR-guided high-intensity focused ultrasound ablation
Marlijne Elisabeth Ikink 1 , Johanna MM van Breugel 1 , Robbert J Nijenhuis 1 , Marianne J Voogt 1 , Maurice AAJ van den Bosch 1 , Koen L Vincken 2 , and Lambertus W Bartels 2
1
Radiology, University Medical Center
Utrecht, Utrecht, Utrecht, Netherlands,
2
Radiology
and Image Sciences Institute, University Medical Center
Utrecht, Utrecht, Utrecht, Netherlands
Diffusion-weighted MRI has been increasingly used to
evaluate gynaecological tumors. Using the intravoxel
incoherent motion (IVIM) approach, diffusion-weighted
sequences can be used to measure both the molecular
movement of water molecules and the microcirculation of
blood in the capillaries. The diffusion coefficient (
D
)
and perfusion fraction (
f
) of uterine fibroids
were determined in relation with their signal intensity
on T2-weighted (T2w) MRI. High-intensity (type 3)
uterine fibroids were found to have a higher diffusion
coefficient
D
than
fibroids with a lower T2w signal-intensity. We were not
able to demonstrate a significant difference in the
perfusion fraction (
f
).
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