Comparison of white matter and gray matter macromolecule resonances between 3 and 7 Tesla
KARIM SNOUSSI 1,2 , JOSEPH S. GILLEN 1,2 , ALENA HORSKA 1,2 , NICOLAAS A.J. PUTS 1,2 , SUBECHHYA PRADHAN 1,2 , RICHARD A.E. EDDEN 1,2 , and PETER B. BARKER 1,2
Russell H. Morgan Department of Radiology
and Radiological Science, Johns Hopkins University,
Baltimore, MD, United States,
Kirby Research Centre, Kennedy Krieger Institute,
Baltimore, MD, United States
Macromolecule (MM) resonances in proton spectra of the
brain are a complicating factor when determining
metabolite concentrations, and also of interest in their
own right in some pathological conditions. To date,
there have been few studies of differences in MM
resonances between gray (GM) and white matter (WM), or
between different field strengths. This abstract
presents results of MM concentrations in two GM and WM
locations, and also compares results between 3 and 7T.
No significant regional or field strength dependencies
were found, however MM resonances (measured in Hz) were
broader at 7T than 3T.
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