Abstract #3747
Reproducibility of the 1D-ISIS localized ST experiment for hepatic Pi-to-ATP reaction rate measurement at 7T
Ladislav Valkovic 1,2 , Martin Gajdosk 1 , Marek Chmelk 1 , Wolfgang Bogner 1 , Ivan Frollo 2 , Stephan Gruber 1 , Siegfried Trattnig 1 , and Martin Krssk 1,3
1
High Field MR Centre, Department of
Biomedical Imaging and Image-guided Therapy, Medical
University of Vienna, Vienna, Austria,
2
Department
of Imaging Methods, Institute of Measurement Science,
Slovak Academy of Sciences, Bratislava, Slovakia,
3
Division
of Endocrinology and Metabolism, Department of Internal
Medicine III, Medical University of Vienna, Vienna,
Austria
Our aim was to test the reproducibility/reliability of
the fast
31
P
saturation transfer (ST)
in
vivo
at
7T for localized measurement of Pi-to-ATP reaction in
the liver. Test-retest measurements of the hepatic ST
experiment and a contamination check of the spectra from
the surrounding muscles were performed. Our data show
only negligible fraction of the abdominal muscle signal
in the liver spectra and the test-retest variation was
very low. Thus we can conclude that fast ST measurements
in the liver at 7T are highly reproducible.
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