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Abstract #3788

Carnosine at 7T: quantification and relaxation times in m. gastrocnemius

Ivica Just Kukurova 1,2 , Martin Krk 1,3 , Marek Chmelik 1 , Martin Gajdok 1 , Siegfried Trattnig 1 , and Ladislav Valkovič 1,4

1 High-field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, 2 Slovak University of Technology, Bratislava, Slovakia, 3 Division of Endocrinology and Metabolism, Department of Internal Medicine III, Vienna, Austria, 4 Department of Imaging Methods, Institute of Measurement Science, Slovak Academy of Sciences, Bratislava, Slovakia

Carnosine in skeletal muscle plays an important role as a buffer for intracellular pH. Its concentration can be measured by proton MRS. Aim of this study was to measure relaxation times of carnosine in m. gastrocnemius in vivo at 7T which was achieved and succesfully applied for quantification of concentration of carnosine. Results will be used for further metabolic studies.

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