Abstract #3845
Normal and Pathologically Altered in vivo 3D Aortic Wall Shear Stress Maps
Pim van Ooij 1 , Wouter V. Potters 2 , Aart J. Nederveen 2 , Bradley D. Allen 1 , Jeremy Collins 1 , James Carr 1 , S. Chris Malaisrie 3 , Michael Markl 1,4 , and Alex J. Barker 1
1
Radiology, Northwestern University, Chicago,
IL, United States,
2
Radiology,
Academic Medical Center, Amsterdam, Netherlands,
3
Medicine-Cardiology,
Northwestern University, Chicago, IL, United States,
4
Biomedical
Engineering, Northwestern University, Chicago, IL,
United States
In this study, a methodology to create 3D WSS vector
maps averaged over multiple subjects in a cohort is
presented and demonstrated in three cohorts: 10 patients
with aortic dilation, 10 patients with aortic valve
stenosis and 10 healthy controls. Significance of the
differences between cohorts were illustrated by P-value
maps. It was found that 13% of the ascending aorta
surface of the dilation map showed significantly lower
WSS than the control map, whereas 54% of the ascending
aorta surface of the stenosis map showed significantly
higher WSS than the control map.
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