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Abstract #3846

Validation of high temporal resolution spiral phase velocity mapping of coronary artery blood flow against Doppler Flowire

Jennifer Keegan 1 , Claire E Raphael 1 , Robin Simpson 1 , Kim Parker 2 , Peter Drivas 3 , Ranil de Silva 4 , Carlo Di Mario 4 , Sanjay Prasad 3 , and David Firmin 3,5

1 Cardiovascular Biomedical Research Unit, Royal Brompton Hospital, London, United Kingdom, 2 Imperial College, London, United Kingdom, 3 Cardiovascular Biomedical Research Unit, Royal Brompton Hospital, United Kingdom, 4 Cardiology, Royal Brompton Hospital, United Kingdom, 5 Imperial College London, United Kingdom

The temporal pattern of coronary flow velocity through the cardiac cycle provides important information about coronary haemodynamics and atherosclerotic disease state. In this study, we compare breath-hold high temporal resolution (19ms) spiral phase velocity mapping of proximal left and right coronary blood flow velocity with invasive gold-standard Doppler Flowire measurements in a small group of patients. As expected, MR velocities are lower than Doppler velocities (by 47% on average) but the temporal flow patterns are similar (R2 = .47 - .91). We conclude that spiral phase velocity mapping has the potential to assess temporal patterns of coronary flow velocity non-invasively.

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