Abstract #3846
Validation of high temporal resolution spiral phase velocity mapping of coronary artery blood flow against Doppler Flowire
Jennifer Keegan 1 , Claire E Raphael 1 , Robin Simpson 1 , Kim Parker 2 , Peter Drivas 3 , Ranil de Silva 4 , Carlo Di Mario 4 , Sanjay Prasad 3 , and David Firmin 3,5
1
Cardiovascular Biomedical Research Unit,
Royal Brompton Hospital, London, United Kingdom,
2
Imperial
College, London, United Kingdom,
3
Cardiovascular
Biomedical Research Unit, Royal Brompton Hospital,
United Kingdom,
4
Cardiology,
Royal Brompton Hospital, United Kingdom,
5
Imperial
College London, United Kingdom
The temporal pattern of coronary flow velocity through
the cardiac cycle provides important information about
coronary haemodynamics and atherosclerotic disease
state. In this study, we compare breath-hold high
temporal resolution (19ms) spiral phase velocity mapping
of proximal left and right coronary blood flow velocity
with invasive gold-standard Doppler Flowire measurements
in a small group of patients. As expected, MR velocities
are lower than Doppler velocities (by 47% on average)
but the temporal flow patterns are similar (R2 = .47 -
.91). We conclude that spiral phase velocity mapping has
the potential to assess temporal patterns of coronary
flow velocity non-invasively.
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