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Abstract #3848

Quantification of 3D Arterial and Portal Venous Blood Flow Distribution in Liver Cirrhosis Patients using 4D Flow MRI

Xi Chen 1 , Michael Markl 1 , Julio Garcia Flores 1 , Susanne Schnell 1 , Kelly Brooke Jarvis 1 , James Carr 1 , Jeremy D. Collins 1 , and Zoran Stankovic 1

1 Department of Radiology, Northwestern University, Chicago, Illinois, United States

4D flow MRI provides valuable information on blood flow velocities with full spatial (3D) and temporal (cardiac cycle) coverage, which can be applied to volumetric and functional evaluation of liver hemodynamics in liver cirrhosis patients. This study reveals mean velocities in portal venous and arterial systems of liver tend to be lower for liver cirrhosis patients and appear to be wider distributed. This result is showed by plotting velocity histograms of healthy and pathologic groups with selected parameters based on sensitivity test. Quantitative analysis of liver hemodynamics using flow-sensitive 4D MRI may be a standardized method to complement the diagnosis in liver cirrhosis.

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