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Abstract #3970

Right ventricular myocardial T1 and extracellular volume fraction (ECV) measurements using high resolution ANGIE T1 mapping

Bhairav Bipin Mehta 1 , Kenneth C Bilchick 2 , Xiao Chen 1 , Michael Salerno 1,2 , and Frederick H Epstein 1,3

1 Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, United States, 2 Department of Medicine, Cardiology Division, University of Virginia, Charlottesville, Virginia, United States, 3 Department of Radiology and Medical Imaging, University of Virginia, Charlottesville, Virginia, United States

T1 mapping is routinely used for quantitative assessment of left ventricular fibrosis. Assessment of fibrosis in thin structures such as the right ventricular (RV) and left atrial walls would be valuable in various disorders. However, MOLLI, the current technique, has limited spatial resolution for these applications. We previously developed a sequence termed ANGIE, which enables high-resolution T1 mapping. In the present study, we investigated T1 mapping of the RV in healthy volunteers and heart failure patients using ANGIE. Using ANGIE, we measured the first RV T1 estimates (98096ms) in healthy volunteers and RV ECV estimates (28.01.6%) in heart failure patients.

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