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Abstract #3971

Diffusion Tensor MRI of the Entire Human Heart in Vivo with Blipped-CAIPI and Simultaneous Multislice Acquisition

Choukri Mekkaoui 1 , Timothy G Reese 2 , Himanshu Bhat 3 , Stephen T Cauley 2 , Marcel P Jackowski 4 , Kawin Setsompop 2 , and David E Sosnovik 5

1 Harvard Medical School - Massachusetts General Hospital, Boston, MA, United States, 2 Athinoula A Martinos center for Biomedical imaging, Boston, United States, 3 Siemens, boston, United States, 4 University of So Paulo, So Paulo, Brazil, 5 Harvard Medical School - Massachusetts General Hospital, Boston, United States

The utilization of cardiac DTI has been limited in part by its temporal inefficiency. Here we show that simultaneous multislice acquisition using the blipped-CAIPI technique can be used to increase coverage and reduce scan time by a factor of 3. In vivo DTI of the entire human heart can be performed with this technique in 40 minutes with acceptable resolution, without interslice gaps, and with excellent image quality. The improved coverage and reduced scan time produced by blipped-CAIPI have the potential to improve the accuracy of cardiac DTI and facilitate its clinical use.

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