Abstract #3979
Imaging and visualization of cardiac muscle microstructure in rats using high-resolution MRI
Silun Wang 1 , Xulei Qin 2 , Xiaodong Zhang 1 , Mary B. Wagner 3 , and Baowei Fei 2,4
1
Yerkes Imaging Center, Yerkes National
Primate Research Center, Emory University, Atlanta, GA,
United States,
2
Department
of Radiology and Imaging Sciences, Emory University,
Atlanta, GA, United States,
3
Department
of Pediatrics, Emory University, Atlanta, GA, United
States,
4
Biomedical
Engineering, Emory University, GA, United States
We analyze the cardiac muscle microstructural
characteristics in rats using SWI and DTI imaging. SWI
provided useful information to explore the anatomical
characteristics of cardiac muscle, including left
ventricle and papillary muscle and the cardiac vascular
system in rats. DTI cardiac muscle tractography
identified the orientation and distributions of cardiac
muscle fibers. The current results are potentially
useful to monitor cardiac muscle pathology including
ischemia induced cardiac muscle damage and abnormal iron
deposit as well as evaluations of treatment effects.
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