Abstract #3980
Three-Dimensional MRI-Based Statistical Shape Model of the Knee in Patients with ACL Injuries
Valentina Pedoia 1 , Drew Lansdown 2 , Paul Jung 1 , C. Benjamin Ma 2 , and Xiaojuan Li 1
1
Department of Radiology and Biomedical
Imaging, UCSF, San Francisco, California, United States,
2
Department
of Orthopedic Surgery, UCSF, San Francisco, California,
United States
This study presents a novel 3D MRI-based method to
analyze the knee bones shape and for the first time
applied the technique to knees with ACL-injuries. A
shape modeling is extracted for tibia and femur using a
set of matched landmarks. Significant shape differences
were found between ACL-injured and control knees at
baseline, and significant differences are detected in
longitudinal shape changes between ACL-injured and
control knees. Bone shape quantification has the
potential to identify specific risk factors for injuries
and to describe novel imaging markers for the
development of post-traumatic OA after an acute injury.
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