Abstract #3981
Patient-reported Outcomes are associated with Cartilage T1ρ and T2 Quantification and Whole-Organ Magnetic Resonance Imaging Score (WORMS) after acute ACL injuries
Yu Zhang 1,2 , Michael Hoppe 1 , Samuel Wu 3 , Martin Kretzschmar 3 , Richard Souza 3 , Benjamin Ma 3 , and Xiaojuan Li 3
1
Radiology, University of California San
Francisco, San Francisco, CA, United States,
2
Department
of Orthopaedic Surgery, The First Hospital of Jilin
University, Changchun, Jllin, China,
3
University
of California San Francisco, CA, United States
Our study is to evaluate the relationship between
cartilage MRI quantification, WORMS (Whole-Organ
Magnetic Resonance Imaging Score) and patient-reported
outcomes after acute ACL injuries. forty-two subjects
with ACL acute ruptured were enrolled. T1ρ and T2 MRI
scan were performed at baseline. Osteoarthritis Outcome
Score (KOOS) questionnaire was filled in by each patient
during the MR visit and WORMS score was graded by
experienced msk radiologists. KOOS has significantly
correlations with T1ρ and T2 quantification in some
compartments of cartilage in tibia and Femoral condyle,
and with several sub-scores in WORMS, such as cartilage
lesion and bone marrow edema. Significant correlations
were observed between KOOS and cartilage T1ρ and T2
after adjusted for age, BMI and time to injury,
indicating an independent relationship between cartilage
damage and patient outcomes after acute injuries. Higher
WORMS scores on cartilage lesion and bone marrow edema,
especially on lateral side of knee joint, are obviously
related with worse patients outcome. It revealed that
the recovery of lateral focal lesion potentially greatly
affected the patients daily living quality.
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