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Abstract #3984

Does prestructural, asymptomatic cartilage degeneration occur in early FAI? A T1rho study.

Gerd Melkus 1 , Kawan S Rakhra 1 , Arturo Cardenas-Blanco 2 , Andrew Speirs 3 , Ian Cameron 1 , Mark E Schweitzer 4 , and Paul E Beaul 5

1 Department of Medical Imaging, The Ottawa Hospital, Ottawa, Ontario, Canada, 2 German Center for Neurodegenerative Diseases, Magdeburg, Germany, 3 Department of Mechanical and Aerospace Engineering, Carleton University, Ottawa, Ontario, Canada, 4 Department of Radiology, Stony Brook University, Brookhaven, New York, United States, 5 Division of Orthopedic Surgery, The Ottawa Hospital, Ottawa, Ontario, Canada

In this study T1rho MRI of hip cartilage was performed in three different subject groups: Controls, asymptomatic subjects with cam deformities (Bumps) and symptomatic (Surgical) cam-type femoroacetabular impingement (FAI) patients. The ratio of T1rho of the anterior to the posterior hip hyaline cartilage in the peripheral weight-bearing region of the joint resulted in statistically significant differences between the Control and the Bump group, the Control and the Surgical group, but not between the Bump and the Surgical group. Quantitative T1rho imaging and T1rho ratio analysis has the potential to detect cartilage proteoglycan loss in subjects with symptomatic cam deformities, prior to development of symptomatic cam-FAI.

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