Abstract #4023
Age-associated Changes in Triceps Surae Muscle Composition and Plantarflexor Strength an MR imaging based Study with Ultra-short Echo-time (UTE) and Fat-Water Quantification of Connective, Adipose and Contractile Tissues.
Robert Csapo 1 , Vadim Malis 2 , Usha Sinha 3 , Jiang Du 4 , and Shantanu Sinha 1
1
Radiology, University of California at San
Diego, San Diego, CA, United States,
2
Physics,
San Diego State University, San Diego, CA, United
States,
3
Physics,
San Diego State University, CA, United States,
4
Radiology,
University of California at San Diego, CA, United States
Aging skeletal muscles are characterized by a
progressing accumulation of intramuscular,
non-contractile tissues. To quantitate the amount of
intramuscular adipose (IMAT) and connective (IMCT)
tissues, MR-based fater-water quantitation (IMAT) and
ultrashort echo time (IMCT) imaging techniques were
applied to the study of the Triceps Surae complex in
young (YW) and senior (SW) women. Both IMAT and IMCT
contents were significantly larger in SW. Additional
measurements of plantarflexor strength and Triceps Surae
volumes suggest that the inclusion of non-contractile
tissues is likely to negatively affect a muscles
intrinsic capacity to generate force at older age.
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