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Abstract #4153

The effect of left hemispherotomy surgery in patient with Rasmussens syndrome using fMRI a case study

Kapil Chaudhary 1 , S SENTHIL KUMARAN 2 , Poodipedi Sarat Chandra 3 , and Manjari Tripathi 1

1 Neurology, All India Institute of Medical Science, New Delhi, Delhi, India, 2 Department of NMR, ALL INDIA INSTITUTE OF MEDICAL SCIENCES, New Delhi, Delhi, India, 3 Neurosurgery, All India Institute of Medical Science, New Delhi, Delhi, India

The localizing language and memory in intractable epilepsy has become increasingly elucidated. We describe semantic noun naming and complex scene working memory dysfunction in a right-handed patient using functional MRI and define clinical correlation with functional imaging. A 10-year-old right-handed girl with Rasmussens syndrome was referred to our institute. Intractable seizures may need to be treated with surgery if the seizure control in the patient is not achieved with medications. Although surgical resection is successful in curing up to 70% of patients, a significant risk of post-operative cognitive decline continues to limit its application. Functional MRI was used to observe the role of language and memory function in this patient.

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