Abstract #4154
Frontal Lobe Interhemispheric Connectivity Changes Associated with a Season of High School Football
Fatemeh Mokhtari 1 , Elizabeth Davenport 1 , Jillan Urban 1 , Naeim Bahrami 1 , Christopher Whitlow 2 , Alex Powers 3 , Joel Stitzel 1 , and Joseph Maldjian 2
1
Biomedical Engineering, Wake Forest
University School of Medicine, Winston Salem, NC, United
States,
2
Radiology,
Wake Forest University School of Medicine, Winston
Salem, NC, United States,
3
Neurosurgery,
Wake Forest University School of Medicine, Winston
Salem, NC, United States
The primary goal of this study is to determine if
cumulative head impacts over a season of high school
football has an effect on frontal lobe interhemispheric
connectivity. In order to explore this relationship a
multiple regression analysis was performed using a
linear model of a score of head impacts vs. pre-post
difference in fMRI connectivity. Results indicate
changes in connectivity of frontal structures in
non-concussed subjects during a season of football.
These findings add to a growing body of literature that
cumulative subconcussive sports-related impacts may have
an effect on the brain function.
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