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Abstract #4163

Capsaicin induced Central Neuronal Sensitization in the MIA model of OA pain

Maryam Abaei 1,2 , Devi Sagar 2,3 , Clair Spicer 3 , Elizabeth G Stockley 2 , Malcolm J.W Prior 4 , Henryk Fass 1 , David A Walsh 2,5 , Victoria Chapman 2,3 , and Dorothee P Auer 1,2

1 Radiological Sciences, Division of Clinical Neurosciences, Nottingham University, Nottingham, Nottinghamshire, United Kingdom, 2 Arthritis Research UK Pain Centre, Nottingham University, Nottingham, Nottinghamshire, United Kingdom, 3 School of Life Sciences, Nottingham University, Nottingham, Nottinghamshire, United Kingdom, 4 School of Medicine, Nottingham University, Nottingham, Nottinghamshire, United Kingdom, 5 Academic Rheumatology, Nottingham University, Nottingham, Nottinghamshire, United Kingdom

Ph-fMRI, Brain, Capsaicin, MIA, Osteoarthritis, Animal, Neuronal, Sensitization

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