Abstract #4188
Lithium effect on functional networks of HIV infected individuals as revealed by Generalized Partial Directed Coherence measures.
Madalina E Tivarus 1 , Britta Pester 2 , Tong Zhu 3 , Christoph Schmidt 2 , Thomas Lehmann 2 , Jianhui Zhong 1 , Lutz Leistritz 2 , and Giovanni Schifitto 1
1
University of Rochester, Rochester, NY,
United States,
2
Institute
of Medical Statistics, Computer Sciences and
Documentation, Jena University Hospital, Friedrich
Schiller University, Jena, Germany,
3
University
of Michigan, Ann Arbor, MI, United States
Generalized Partial Directed Coherence (gPDC) was
applied on fMRI data to evaluate changes in functional
networks and their connectivity in HIV infected
individuals treated with lithium for HIV-associated
cognitive impairment. GPDC analysis shows that lithium
affected functional connectivity and it provides a
paradigm to investigate functional and anatomical
interrelationships in the context of clinical changes.
Therefore, applying gPDC on functional MRI data provides
an opportunity to further dissect the functional changes
observed in relevant networks affected by the
intervention.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
