Abstract #4196
CBF-based Modular Architecture Derived from ASL MRI
Feng-Xian Yan 1 , David D. Shin 2 , Chi-Jen Chen 1 , Thomas T. Liu 2 , and Ho-Ling Liu 3
1
Department of Radiology, Taipei Medical
University - Shuang Ho Hospital, New Taipei City,
Taiwan,
2
Center
for Functional MRI and Department of Radiology,
University of California, San Diego, La Jolla, CA,
United States,
3
Department
of Medical Imaging and Radiological Sciences, Chang Gung
University, Taoyuan, Taiwan
This study aimed to investigate the perfusion-based
modular architecture for the bilateral anterior, middle,
and posterior cerebral artery (ACA, MCA, and PCA)
territories, and default mode network (DMN). Whole-brain
CBF maps from 116 healthy subjects, based on arterial
spin labeling measurements, were included for the
analysis. Brain regions exhibited significantly
correlated CBF variations among subjects were identified
by comparing each area in the AAL template with the seed
region. The results demonstrated that significant short-
and long-range connections were found in these
territories and DMN. This study provides a preliminary
result of intrinsic CBF modularity of the human brain.
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